Hi Raju,
Is the Keysight scope using a math function and the Agilent using no math? This would explain the negative voltage. It does not explain the difference in current.
Can you use the same scope (Agilent would be preferred) on both the actual and simulated loads?
Please capture the current, voltage on the outputs, and the voltage on the sense pin if possible. If not, please capture the current and voltage on the sense pin.